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Spent Media Analysis

Spedia-NMR™

Spedia-NMR™ method is rapid, robust, cost-efficient and outperforms LC-based methods on all counts. A minimal sample requirement (typically 1 ml) ensures quantitative results within 2 to 4 weeks.

 

Spent media analysis examines:

  • Spedia-NMR™: 50 analytes such as amino acids, saccharides and metabolites analysis
  • Water-soluble vitamins analysis by LC-MS
  • Elements and trace metals analysis by ICP-OES
  • Surfactants
  • Buffers (HEPES, TRIS)
  • For CHO, bacterial, yeast and insect cells

Contact us for the full analytic list.

 

Improve your bioprocess with Spedia-PredictTM

Spedia-Predict™ is an innovative solution to evaluate performance variability and develop predictive models for your specific bio-manufacturing process.

Spedia-Predict™ integrates our expertise in high-end analytics and chemometrics (incl. Spedia-NMR™, NMR fingerprinting, LC-MS profiling and ICP-OES elemental analysis) to rapidly detect and identify parameters correlating to bioprocess variability. With a combination of critical markers we develop predictive models to reach performance consistency from batch-to-batch. Develop your bioprocess in line with Quality-by-Design. Our data will help you get in control.

 

Get in control

  • Predict and prevent:
    • Eliminate performance variability.
    • Profiling of raw materials: Select the right raw materials supplier.
  • Save time and costs:
    • Kick out cell based assays: faster turnaround.
  • Optimize performance:
    • Improved characterization to optimize your bioprocess.
    • Bioprocess optimization in line with Quality-by-Design.
    • Monitor performance in small and large scale processes: get a grip on scaling!

 

And obtain superior process flows

  • Discard low-performing lots in bioprocesses.
  • Detect parameters affecting cell viability.
  • Develop predictive models for superior quality of the end-product

 

bioprocess variability testing    amino acid analysis    spent media analysis 

 

Read our flyer 'Spent Media and Complex Raw Material Analysis' to learn more about our services. Contact us to discuss your process and the ways to improve.